Let¡¯s face it, organic chemistry can seem difficult to learn, COA of Formula: C5H5ClN2, Especially from a beginner¡¯s point of view. Like 6298-19-7, Name is 2-Chloropyridin-3-amine, molecular formula is C9H12O3, belongs to thiomorpholine compound. In a document, author is Gong, Minghua, introducing its new discovery.
Facile Synthesis of Polysubstituted Indolizines via One-Pot Reaction of 1-Acetylaryl 2-Formylpyrroles and Enals
An efficient method for the synthesis of polysubstituted indolizines has been developed based on formal [4+2] annulation of 1-acetylaryl 2-formylpyrroles with enals, followed by oxidative aromatization. Pyridine-type six-membered rings were constructed in this transformation. This transition metal-free reaction features mild reaction conditions, a broad substrate scope, and excellent functional group tolerance. Notably, the formyl group is well tolerated under reaction conditions.
If you are hungry for even more, make sure to check my other article about 6298-19-7, COA of Formula: C5H5ClN2.
Reference:
Pyridine – Wikipedia,
,Pyridine | C5H5N – PubChem