Pulcini, Alberto; Bollain, Juan; Sanz-Sanchez, Ignacio; Figuero, Elena; Alonso, Bettina; Sanz, Mariano; Herrera, David published the artcile< Clinical effects of the adjunctive use of a 0.03% chlorhexidine and 0.05% cetylpyridinium chloride mouth rinse in the management of peri-implant diseases: A randomized clinical trial>, Safety of 1-Hexadecylpyridin-1-ium chloride, the main research area is Campylobacter Prevotella preimplant disease chlorhexidine cetylpyridium; chlorhexidine; dental implant; mouth rinse; peri-implant diseases; peri-implant mucositis.
To evaluate the efficacy of a 0.03% chlorhexidine and 0.05% cetylpyridinium chloride mouth rinse, as an adjunct to professionally and patient-administered mech. plaque removal, in the treatment of peri-implant mucositis (PiM). Patients displaying PiM in, at least, one implant were included in this randomized, double-blinded, clin. trial. Subjects received professional prophylaxis (baseline and 6 mo) and were instructed to regular oral hygiene practices and to rinse, twice daily, with the test or placebo mouth rinses, during one year. Clin., radiog. and microbiol. outcomes were evaluated at baseline, 6 and 12 mo. Disease resolution was defined as absence of bleeding on probing (BOP). Data were analyzed by repeated measures ANOVA, Students t and chi-square tests. Fifty-four patients were included and 46 attended the final visit (22 in control and 24 in test group). In the test group, there was a 24.49% greater reduction in BOP at the buccal sites (95% confidence interval [3.65-45.34%]; p = 0.002) than in controls. About 58.3% of test implants and 50% controls showed healthy peri-implant tissues at final visit (p > 0.05). The use of the test mouth rinse demonstrated some adjunctive benefits in the treatment of PiM. Complete disease resolution could not be achieved in every case.
Journal of Clinical Periodontology published new progress about Campylobacter (rectus). 123-03-5 belongs to class pyridine-derivatives, and the molecular formula is C21H38ClN, Safety of 1-Hexadecylpyridin-1-ium chloride.