In 2019,Chemical Communications (Cambridge, United Kingdom) included an article by Ragupathi, Ayyakkannu; Sagadevan, Arunachalam; Charpe, Vaibhav Pramod; Lin, Chun-Cheng; Hwu, Jih-Ru; Hwang, Kuo Chu. Reference of 4-Ethynylpyridine. The article was titled 《Visible-light-driven copper-catalyzed aerobic oxidative cascade cyclization of N-tosylhydrazones and terminal alkynes: regioselective synthesis of 3-arylcoumarins》. The information in the text is summarized as follows:
Regioselective green synthesis of 3-arylcoumarins I [R1 = H, 6-Me, 6-Br, etc.; R2 = H, 3-MeOC6H4, 4-Py, etc.; R3 = H, Me, Ph] as sustainable process was carried out via visible-light-driven copper catalyzed aerobic oxidative cascade cyclization of N-tosylhydrazones with terminal alkynes. This operationally simple methodol. was successfully proceeded well to afford biol. active compounds, such as monoamine oxidase B inhibitor I [R1 = 6-Me; R2 = 3-MeOC6H4; R3 = H] and horseradish peroxidase inhibitor I [R1 = 6-OH; R2 = 2-HOC6H4; R3 = H] in satisfactory yields under mild conditions. In the experiment, the researchers used many compounds, for example, 4-Ethynylpyridine(cas: 2510-22-7Reference of 4-Ethynylpyridine)
4-Ethynylpyridine(cas: 2510-22-7) belongs to pyridine. In industry and in the lab, pyridine is used as a reaction solvent, particularly when its basicity is useful, and as a starting material for synthesizing some herbicides, fungicides, and antiseptics.Reference of 4-Ethynylpyridine