On March 31, 2010, Rajalakshmi, G.; Damodharan, N.; Chaudhary, Abhinav; Maheswara Reddy, D. published an article.COA of Formula: C20H24N2O4 The title of the article was Formulation and evaluation of Orodispersible tablets of Pheniramine maleate. And the article contained the following:
In the present study an attempt has been made to formulate Pheniramine maleate a selective H1 receptor antagonist into orodispersible tablet. The tablets were prepared by direct compression method using super disintegrants like croscarmellose sodium, crospovidone, sodium starch glycollate, low hydroxyl pr cellulose and pre gelatinized starch in different ratios. The blend was examined for various pre compression parameters. Tablets were evaluated by measuring hardness, friability, content uniformity, weight variation and drug release pattern. All the tablets met the pharmacopoeial requirements for phys. tests. Almost in all the formulations with increase in concentration of superdisintegrants, the drug release was rapid. Stability studies were also performed. Dissolution studies indicated that the tablets containing crospovidone and croscarmellose sodium showed rapid dissolution compared to other disintegrants releasing almost 100% of the drug in six minutes. The experimental process involved the reaction of N,N-Dimethyl-3-phenyl-3-(pyridin-2-yl)propan-1-amine maleate(cas: 132-20-7).COA of Formula: C20H24N2O4
The Article related to pheniramine maleate orodispersible tablet, Pharmaceuticals: Formulation and Compounding and other aspects.COA of Formula: C20H24N2O4