Reich, Marvin F.’s team published research in Journal of Medicinal Chemistry in 32 | CAS: 18437-58-6

Journal of Medicinal Chemistry published new progress about 18437-58-6. 18437-58-6 belongs to pyridine-derivatives, auxiliary class Pyridine,Amine, name is 4-Amino-2-picoline, and the molecular formula is C6H8N2, Recommanded Product: 4-Amino-2-picoline.

Reich, Marvin F. published the artcilePyrido[3,4-e]-1,2,4-triazines and related heterocycles as potential antifungal agents, Recommanded Product: 4-Amino-2-picoline, the publication is Journal of Medicinal Chemistry (1989), 32(11), 2474-85, database is CAplus and MEDLINE.

The preparation and biol. activities of a series of pyrido[3,4-e]-1,2,4-triazines I (R = H, alkyl, CF3, cycloalkyl, Ph, substituted Ph, 2-naphthyl, pyridyl, CH:CHNR12, where NR12 = dimethylamino, piperidino, or 4-methylpiperazino), 1,2,4-triazino[5,6-c]quinolines II (R = H, Me, 4-pyridyl), and related fused triazines are described. Methyl, amino, and acylamino substituents were placed in the pyridyl ring of the former system. In agar dilution assays, active compounds in this series, e.g., I (R = H, Me, CH2OPh, Ph, 4-FC6H4, 3-FC6H4, 3,4-F2C6H3, 3-, 4-pyridyl) inhibited strains of Candida, Aspergillus, Mucor, and Trichophyton species at MIC’s of ≤16μg/mL.

Journal of Medicinal Chemistry published new progress about 18437-58-6. 18437-58-6 belongs to pyridine-derivatives, auxiliary class Pyridine,Amine, name is 4-Amino-2-picoline, and the molecular formula is C6H8N2, Recommanded Product: 4-Amino-2-picoline.

Referemce:
https://en.wikipedia.org/wiki/Pyridine,
Pyridine | C5H5N – PubChem