Reisenbauer, Julia C. published the artcileDevelopment of an Operationally Simple, Scalable, and HCN-Free Transfer Hydrocyanation Protocol Using an Air-Stable Nickel Precatalyst, Computed Properties of 91-02-1, the publication is Organic Process Research & Development (2022), 26(4), 1165-1173, database is CAplus.
Herein, HCN-free transfer hydrocyanation of alkenes and alkynes that employed com. available aliphatic nitriles R1CC(CN)R1 [R1 = Ph, 2-MeC6H4, 4-PhC6H4, etc.; R2 = H; R1R2 = (CH2)6] and alkenyl nitriles R1C=C(CN)R1 [R1 = nPr, nBu, SiMe3 R2 = nPr, nBu, Ph] as sacrificial HCN donors in combination with a catalytic amount of air-stable and inexpensive NiCl2 as a precatalyst and a cocatalytic Lewis acid was reported. The scalability and robustness of the catalytic process were demonstrated by the hydrocyanation of α-methylstyrene on a 100 mmol scale (11.4 g of product obtained) using 1 mol % of the Ni catalyst. In addition, the feasibility of the dehydrocyanation protocol using the air-stable Ni(II) precatalyst and norbornadiene as a sacrificial acceptor was showcased by the selective conversion of an aliphatic nitrile into the corresponding alkene.
Organic Process Research & Development published new progress about 91-02-1. 91-02-1 belongs to pyridine-derivatives, auxiliary class Pyridine,Benzene,Ketone, name is Phenyl(pyridin-2-yl)methanone, and the molecular formula is C12H9NO, Computed Properties of 91-02-1.
Referemce:
https://en.wikipedia.org/wiki/Pyridine,
Pyridine | C5H5N – PubChem