《Fluorine-substituted tetracationic ABAB-phthalocyanines for efficient photodynamic inactivation of Gram-positive and Gram-negative bacteria》 was written by Revuelta-Maza, Miguel A.; Gonzalez-Jimenez, Patricia; Hally, Cormac; Agut, Montserrat; Nonell, Santi; de la Torre, Gema; Torres, Tomas. Recommanded Product: 4-EthynylpyridineThis research focused onzinc fluorine substituted phthalocyanine complex preparation fluorescence; antibacterial activity photodynamic therapy zinc phthalocyanine; Amphiphile; Bacteria; Cationic; Photodynamic inactivation; Phthalocyanine. The article conveys some information:
Herein, the authors report the synthesis and characterization of new amphiphilic phthalocyanines (Pcs), the study of their singlet oxygen generation capabilities, and biol. assays to determine their potential as photosensitizers for photodynamic inactivation of bacteria. In particular, Pcs with an ABAB geometry (A and B refer to differently substituted isoindole constituents) have been synthesized. These mols. are endowed with bulky bis(trifluoromethylphenyl) groups in two facing isoindoles, which hinder aggregation and favor singlet oxygen generation, and pyridinium or alkylammonium moieties in the other two isoindoles. In particular, two water-soluble Pc derivatives (PS-1 and PS-2) proved to be efficient in the photoinactivation of S. aureus and E. coli, selected as models of Gram-pos. and Gram-neg. bacteria. After reading the article, we found that the author used 4-Ethynylpyridine(cas: 2510-22-7Recommanded Product: 4-Ethynylpyridine)
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