Romano, Sonia published the artcileDrug shortages in community pharmacies: Impact on patients and on the health system, Quality Control of 21829-25-4, the publication is Journal of the American Pharmacists Association (2022), 62(3), 791-799.e2, database is CAplus and MEDLINE.
Worldwide, drug shortages are a critical public health concern. Consequences range from inconvenience and distress to more serious concerns related to neg. clin., humanistic and economic outcomes. This study aimed to investigate the impact of drug shortages at the community pharmacies on patients and on the health system in Portugal. A national, cross-sectional, multicenter study was conducted in Portuguese community pharmacies during Apr. 2019. The proportion of patients reporting drug shortages, types of drugs affected and consequent economic burden to patients and the health system were estimated Regional and urban setting stratification was performed.A total of 71.1% of pharmacies participated in the study and 22,830 patient surveys were retrieved. About 52.2% of patients experienced a drug shortage in the past 12 mo; 21.5% had to see a physician to change the prescription and 5.7% declared treatment discontinuation because of this shortage. The estimated economic impact of shortages related to addnl. physician appointments varied between euro2.1-euro4.4 million for patients and euro35.3-euro43.8 million for the National Health Service. Drug shortages were mostly felt in rural and inner regions and least felt in the islands. This national study showed that community pharmacy drug shortages are a national problem with neg. consequences on patients and the health system, which need to be tackled and mitigated.
Journal of the American Pharmacists Association published new progress about 21829-25-4. 21829-25-4 belongs to pyridine-derivatives, auxiliary class Membrane Transporter/Ion Channel,Calcium Channel, name is Dimethyl 2,6-dimethyl-4-(2-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate, and the molecular formula is C17H18N2O6, Quality Control of 21829-25-4.
Referemce:
https://en.wikipedia.org/wiki/Pyridine,
Pyridine | C5H5N – PubChem