Roy, Sebastien A.; Zgheib, Jose; Zhou, Cuihan; Arndtsen, Bruce A. published an article in 2021. The article was titled 《Palladium catalyzed synthesis of indolizines via the carbonylative coupling of bromopyridines, imines and alkynes》, and you may find the article in Chemical Science.Formula: C6H6BrN The information in the text is summarized as follows:
Authors report herein the development of a palladium-catalyzed, multicomponent synthesis of indolizines. The reaction proceeds via the carbonylative formation of a high energy, mesoionic pyridine-based 1,3-dipole, which can underwent spontaneous cycloaddition with alkynes. Overall, this provides a route to prepare indolizines in a modular fashion from combinations of com. available or easily generated reagents: 2-bromopyridines, imines and alkynes. After reading the article, we found that the author used 2-Bromo-5-methylpyridine(cas: 3510-66-5Formula: C6H6BrN)
2-Bromo-5-methylpyridine(cas: 3510-66-5) belongs to pyridine. Pyridines form stable salts with strong acids. Pyridine itself is often used to neutralize acid formed in a reaction and as a basic solvent. Formula: C6H6BrN