SDS of cas: 29682-15-3In 1982 ,《Reactions of haloquinolizinium bromides with diethylamine》 appeared in Journal of Heterocyclic Chemistry. The author of the article were Sanders, Georgine M.; Van Dijk, M.; Van der Plas, H. C.. The article conveys some information:
The reactions of quinolizinium bromide (QB) and its four monobromo derivatives with diethylamine have been investigated. For Br in position 2 or 4, substitution is the main process, whereas for Br in positions 1 and 3 quant. ring opening is found. The substituted pyridylbutadienes formed by ring opening, are cis-trans-butadienes, which isomerize into the all-trans forms. The steric course of the ring opening is explained. The results came from multiple reactions, including the reaction of Methyl 5-bromopicolinate(cas: 29682-15-3SDS of cas: 29682-15-3)
Methyl 5-bromopicolinate(cas: 29682-15-3) belongs to pyridine. Pyridine and pyridine-derived structures are privileged pharmacophores in medicinal chemistry and an essential functionality for organic chemists. As the prototypical π-deficient heterocycle, pyridine illustrates distinctive chemistry as both substrate and reagent. SDS of cas: 29682-15-3