Importance of dual resonance susceptibilities for pi-donor and pi-acceptor substituents regarding a quantitative description of substituent effects. The case of basicity of pyridine N-oxides was written by Sawada, Masami;Yukawa, Yasuhide;Hanafusa, Terukiyo;Tsuno, Yuho. And the article was included in Tetrahedron Letters in 1980.COA of Formula: C7H9NO This article mentions the following:
Basicities of 21 m– and p-substituted pyridine N-oxides in H2O were successfully described by the generalized LArSR equation, which potentially allows a dual resonance effect. In the experiment, the researchers used many compounds, for example, 3,5-Dimethylpyridine 1-oxide (cas: 3718-65-8COA of Formula: C7H9NO).
3,5-Dimethylpyridine 1-oxide (cas: 3718-65-8) belongs to pyridine derivatives. The ring atoms in the pyridine molecule are sp2-hybridized. The nitrogen is involved in the 锜?bonding aromatic system using its unhybridized p orbital. The lone pair is in an sp2 orbital, projecting outward from the ring in the same plane as the 锜?bonds. Halopyridines are particularly attractive synthetic building blocks in a variety of cross-coupling methods, including the Suzuki-Miyaura cross-coupling reaction.COA of Formula: C7H9NO