Oxygen-17 NMR spectroscopy: σI dependence for the substituent chemical shifts of 3-substituted pyridine 1-oxides was written by Sawada, Masami;Takai, Yoshio;Kimura, Satoshi;Yamano, Satoshi;Misumi, Soichi;Hanafusa, Terukiyo;Tsuno, Yuho. And the article was included in Tetrahedron Letters in 1986.Application In Synthesis of 3,5-Dimethylpyridine 1-oxide This article mentions the following:
17O NMR spectra were measured at natural abundance in DMSO for a series of 3-substituted pyridine 1-oxides, and their substituent chem. shifts were correlated with σI substituent constants and not with ΔpKa values. In the experiment, the researchers used many compounds, for example, 3,5-Dimethylpyridine 1-oxide (cas: 3718-65-8Application In Synthesis of 3,5-Dimethylpyridine 1-oxide).
3,5-Dimethylpyridine 1-oxide (cas: 3718-65-8) belongs to pyridine derivatives. The ring atoms in the pyridine molecule are sp2-hybridized. The nitrogen is involved in the π-bonding aromatic system using its unhybridized p orbital. The lone pair is in an sp2 orbital, projecting outward from the ring in the same plane as the σ bonds. Pyridine, its benzo and pyridine-based compounds play diverse roles in organic chemistry. Pyridine-based materials are valued for their optical and physical properties as well as their medical potential. Application In Synthesis of 3,5-Dimethylpyridine 1-oxide