Scarry, Sarah M. published the artcileSynthesis of Kappa Opioid Antagonists Based On Pyrrolo[1,2-α]quinoxalinones Using an N-Arylation/Condensation/Oxidation Reaction Sequence, Application of 2-Bromopyridin-3-amine, the publication is Journal of Organic Chemistry (2016), 81(21), 10538-10550, database is CAplus and MEDLINE.
The quinoxaline and quinoxalinone family of N heterocycles is present in mols. of therapeutic relevance for diverse applications ranging from infectious diseases to neuroscience targets. Here, the authors describe a general synthetic sequence to afford pyrrolo[1,2-α]pyrazinones from com. available starting materials and their use in preparing potential kappa opioid receptor antagonists. The biol. data obtained from the latter set of compounds is briefly presented and discussed.
Journal of Organic Chemistry published new progress about 39856-58-1. 39856-58-1 belongs to pyridine-derivatives, auxiliary class Pyridine,Bromide,Amine, name is 2-Bromopyridin-3-amine, and the molecular formula is C5H5BrN2, Application of 2-Bromopyridin-3-amine.
Referemce:
https://en.wikipedia.org/wiki/Pyridine,
Pyridine | C5H5N – PubChem