An article Palladium-Catalyzed Formal Hydroalkylation of Aryl-Substituted Alkynes with Hydrazones WOS:000537524300001 published article about C-H BONDS; OLEFIN SYNTHESIS; ENANTIOSELECTIVE SYNTHESIS; INTERNAL ALKYNES; ALDEHYDES; ALKENYLATION; CARBANIONS; 1,3-DIENES; ALCOHOLS; ALKENES in [Yu, Lin; Lv, Leiyang; Qiu, Zihang; Chen, Zhangpei; Liang, Yu-Feng; Li, Chao-Jun] McGill Univ, Dept Chem, 801 Sherbrooke St West, Montreal, PQ H3A 0B8, Canada; [Yu, Lin; Lv, Leiyang; Qiu, Zihang; Chen, Zhangpei; Liang, Yu-Feng; Li, Chao-Jun] McGill Univ, FRQNT Ctr Green Chem & Catalysis, 801 Sherbrooke St West, Montreal, PQ H3A 0B8, Canada; [Yu, Lin; Lv, Leiyang; Tan, Ze] Hunan Univ, Coll Chem & Chem Engn, State Key Lab Chemo Biosensing & Chemometr, Changsha 410082, Peoples R China in 2020.0, Cited 62.0. The Name is 3-Pyridinecarboxaldehyde. Through research, I have a further understanding and discovery of 500-22-1. SDS of cas: 500-22-1
We have developed an unprecedented Pd-catalyzed formal hydroalkylation of alkynes with hydrazones, which are generated in situ from naturally abundant aldehydes, as both alkylation reagents and hydrogen donors. The hydroalkylation proceeds with high regio- and stereoselectivity to form (Z)-alkenes, which are more difficult to generate compared to (E)-alkenes. The reaction is compatible with a wide range of functional groups, including hydroxy, ester, ketone, nitrile, boronic ester, amine, and halide groups. Furthermore, late-stage modifications of natural products and pharmaceutical derivatives exemplify its unique chemoselectivity, regioselectivity, and synthetic applicability. Mechanistic studies indicate the possible involvement of Pd-hydride intermediates.
SDS of cas: 500-22-1. About 3-Pyridinecarboxaldehyde, If you have any questions, you can contact Yu, L; Lv, LY; Qiu, ZH; Chen, ZP; Tan, Z; Liang, YF; Li, CJ or concate me.
Reference:
Pyridine – Wikipedia,
,Pyridine | C5H5N – PubChem