Seibertz, Fitzwilliam published the artcileSingle-cell optical action potential measurement in human induced pluripotent stem cell-derived cardiomyocytes, Related Products of pyridine-derivatives, the main research area is singlecell optical action potential human pluripotent stem cell cardiomyocyte.
Conventional intracellular microelectrode techniques to quantify cardiomyocyte electrophysiol. are extremely complex, labor intensive, and typically carried out in low throughput. Rapid and ongoing expansion of induced pluripotent stem cell (iPSC) technol. presents a new standard in cardiovascular research and alternate methods are now necessary to increase throughput of electrophysiol. data at a single cell level. VF2.1Cl is a recently derived voltage sensitive dye which provides a rapid single channel, high magnitude response to fluctuations in membrane potential. It possesses kinetics superior to those of other existing voltage indicators and makes available functional data equivalent to that of traditional microelectrode techniques. Here, we demonstrate simplified, non-invasive action potential characterization in externally paced human iPSC derived cardiomyocytes using a modular and highly affordable photometry system.
Journal of Visualized Experiments published new progress about Absorption. 21829-25-4 belongs to class pyridine-derivatives, name is Dimethyl 2,6-dimethyl-4-(2-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate, and the molecular formula is C17H18N2O6, Related Products of pyridine-derivatives.