2,5- and 5,6-Dihalonicotinic acids and their precursors. II was written by Setliff, Frank L.;Rankin, Gary O.. And the article was included in Journal of Chemical and Engineering Data in 1972.Category: pyridine-derivatives This article mentions the following:
2-Chloro- and 2-bromo-5-fluoronicotinic acid and 6-chloro- and 6-bromo-5-fluoronicotinic acid were prepared (25-68%) by oxidation of dihalo-3-picolines. Spectral data for the acids, two of the dihalopicolines, and their amino-halo precursors was determined In the experiment, the researchers used many compounds, for example, 2-Bromo-5-fluoro-3-methylpyridine (cas: 38186-85-5Category: pyridine-derivatives).
2-Bromo-5-fluoro-3-methylpyridine (cas: 38186-85-5) belongs to pyridine derivatives. Pyridine’s the lone pair does not contribute to the aromatic system but importantly influences the chemical properties of pyridine, as it easily supports bond formation via an electrophilic attack. Halopyridines are particularly attractive synthetic building blocks in a variety of cross-coupling methods, including the Suzuki-Miyaura cross-coupling reaction.Category: pyridine-derivatives