《Metal-Free Radical-Mediated C(sp3)-H Heteroarylation of Alkanes》 was published in Organic Letters in 2020. These research results belong to Shao, Xin; Wu, Xinxin; Wu, Shuo; Zhu, Chen. COA of Formula: C6H4N2 The article mentions the following:
Herein we disclose a metal-free, N/O-centered radical-promoted Minisci reaction, in which the coupling of various heteroarenes with simple alkanes proceeds under mild conditions. The reaction conditions are neutral; no extra acid is added to preactivate N-heteroarenes in the Minisci reaction. The N-/O-centered radicals are generated directly from amide (TsNHMe) or alc. (CF3CH2OH) under visible-light irradiation This green and eco-friendly synthetic process may find potential use in medicinal chem. The experimental part of the paper was very detailed, including the reaction process of 4-Cyanopyridine(cas: 100-48-1COA of Formula: C6H4N2)
4-Cyanopyridine(cas: 100-48-1) belongs to pyridine. Pyridine is widely used in the precursor to agrochemicals and pharmaceuticals. Also, it is used as an important reagent and organic solvent.COA of Formula: C6H4N2