Reference of 113682-56-7, Researchers who often do experiments know that organic synthesis is a process of preparing more complex target molecules from simple raw materials through one or more chemical reactions. Generally, it requires fewer steps,and cheap raw materials. 113682-56-7, name is 1,4-Di(pyridin-4-yl)benzene. A new synthetic method of this compound is introduced below.
Comparative compound 2 is synthesized by the following method. 0.5 g (2.2 mmol) of 1,4-di(4-pyridyl)benzene, 1.3 g (6.6 mmol) of cyanobenzyl bromide, and 20 ml of DMF were placed in a 100 ml eggplant-shaped flask, Followed by stirring at 100 C. for 8 hours. After completion of the reaction, the reaction mixture was concentrated under reduced pressure, the concentrated system was dispersed in ethyl acetate and washed, and the precipitated crystals were filtered and washed with ethyl acetate to obtain 1.0 g (yield 73% ) Was obtained.Subsequently, 0.5 g (0.8 mmol) of the Br compound of Comparative Compound 2 was changed to an aqueous solution, and an aqueous solution of 0.4 g (2.5 mol) of ammonium hexafluorophosphate was added dropwise, followed by stirring for 2 hours. After completion of the reaction, the precipitated white crystals were filtered, washed with water and dried at 50 C. under reduced pressure to obtain 0.48 g (yield 80%) of Comparative Compound 2
These compound has a wide range of applications. It is believed that with the continuous development of the source of the synthetic route,113682-56-7, its application will become more common.
Reference:
Patent; CANON INCORPORATED; TAMURA, TETSUYA; IGAWA, SATOSHI; YAMADA, KENJI; (27 pag.)JP2017/197477; (2017); A;,
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