Application of 153034-88-9, The major producers of chemicals have been the Europe, Japan and China. Due to the growing call for a cleaner, greener environment, people will have to find innovative ways to maintain their relevance. Here is a compound 153034-88-9, name is 2-Chloro-4-iodo-3-methylpyridine. This compound has unique chemical properties. The synthetic route is as follows.
Step 15-1. 4-Iodo-N,N,3-trimethylpyridine-2-amine (Compound 15b) A DMF (7.9 mL) solution of 2-chloro-4-iodo-3-methylpyridine (Compound 15a, 500 mg, 1.97 mmol), N-ethyl-N-propan-2-ylpropane-2-amine (0.515 mL, 2.96 mmol), and a THF solution (2.96 mL, 5.92 mmol) of 2M dimethylamine was stirred at 130 C. for 17 h., then the solution was cooled to room temperature and formic acid (0.4 mL) was added. The solution was purified by reversed-phase chromatography (acetonitrile/water, 0.1% formic acid) to obtain the titled Compound 15b (258 mg, yield 50%) as a light brown solution.
While traditionally a conservative industry, chemical producers will need to modernize their PR strategies to stay relevant.we look forward to future research findings about 153034-88-9, 2-Chloro-4-iodo-3-methylpyridine.
Reference:
Patent; Chugai Seiyaku Kabushiki Kaisha; YOSHINO, Hitoshi; TSUCHIYA, Satoshi; MATSUO, Atsushi; SATO, Tsutomu; NISHIMOTO, Masahiro; OGURI, Kyoko; OGAWA, Hiroko; NISHIMURA, Yoshikazu; FURUTA, Yoshiyuki; KASHIWAGI, Hirotaka; HORI, Nobuyuki; KAMON, Takuma; SHIRAISHI, Takuya; YOSHIDA, Shoshin; KAWAI, Takahiro; TANIDA, Satoshi; AOKI, Masahide; (169 pag.)US2019/225604; (2019); A1;,
Pyridine – Wikipedia,
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