Reference of 942189-65-3, As we all know, there are many different methods for the synthesis of a compound, and people can choose the synthesis method that suits their own laboratory according to the actual situation. 942189-65-3, name is 2-(6-Bromopyridin-3-yl)pyrimidine, molecular formula is C9H6BrN3, The compound is widely used in many fields, so it is necessary to find a new synthetic route. The downstream synthesis method of this compound is introduced below.
A mixture of 2-(6-Bromo-pyridin-3-yl)-pyrimidine 76 (100mg, 0.425mmol), potassium carbonate (100mg,0.724mmol), and piperazine (100mg,1.16mmol) in DMF’ (5ml), were stirred at 1000C for 1 hour. The reaction was cooled, solvent evaporated^/ – under reduced pressure, and the residue dissolved in MeCI2 (150ml), washed with H2O (50ml),dried over MgSO4,filtered and evaporated solvent yielding title product 77 as a white solid (100mg,98%). ESMS (MH, 242).
While traditionally a conservative industry, chemical producers will need to modernize their PR strategies to stay relevant.we look forward to future research findings about 942189-65-3, 2-(6-Bromopyridin-3-yl)pyrimidine.
Reference:
Patent; SCHERING CORPORATION; WO2008/156739; (2008); A1;,
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem