Share a compound : 26510-52-1

At the same time, in my other blogs, there are other synthetic methods of this type of compound,26510-52-1, Ethyl 3-oxo-3-(pyridin-2-yl)propanoate, and friends who are interested can also refer to it.

Adding a certain compound to certain chemical reactions, such as: 26510-52-1, Ethyl 3-oxo-3-(pyridin-2-yl)propanoate, can increase the reaction rate and produce products with better performance than those obtained under traditional synthetic methods. Here is a downstream synthesis route of the compound, HPLC of Formula: C10H11NO3, blongs to pyridine-derivatives compound. HPLC of Formula: C10H11NO3

3-Oxo-3-pyridin-2-yl-propionic acid ethyl ester (500 mg, 2.59 mmol) and ethylhydrazine oxalate (389 mg, 2.59 mmol) was dissolved in EtOH, and stirred at 80 C. Upon completion, the EtOH was removed and triturated with Et2O to give 2-Ethyl-5-pyridin-2-yl-2H-pyrazol-3-ol (200 mg, 40%) as a white solid.

At the same time, in my other blogs, there are other synthetic methods of this type of compound,26510-52-1, Ethyl 3-oxo-3-(pyridin-2-yl)propanoate, and friends who are interested can also refer to it.

Reference:
Patent; Alam, Muzaffar; Du Bois, Daisy Joe; Hawley, Ronald Charles; Kennedy-Smith, Joshua; Minatti, Ana Elena; Palmer, Wylie Solang; Silva, Tania; Wilhelm, Robert Stephen; US2011/71150; (2011); A1;,
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem