Electric Literature of 13296-04-3 ,Some common heterocyclic compound, 13296-04-3, molecular formula is C11H10N2, its traditional synthetic route has been very mature, but the traditional synthetic route has various shortcomings, such as complicated route, low yield, poor purity, etc., below Introduce a new synthetic route.
(13-1-1) Synthesis of 2-hydrazinopyridine-5-carboxylic acid In an amount of 50 g of 6-chloronicotinic acid was mixed with 300 mL of n-butanol, added with 80 g of hydrazine monohydrate and refluxed by heating for 10 hours. The reaction mixture was cooled and poured into 500 mL of diluted hydrochloric acid. The deposited crystal was collected by filtration, washed with water and dried to obtain the desired substance. Yield: 44.2 g, 90.9%.
In the field of chemistry, the synthetic routes of compounds are constantly being developed and updated. I will also mention this compound in other articles. 13296-04-3, 4-(Pyridin-4-yl)aniline, other downstream synthetic routes, hurry up and to see.
Reference:
Patent; FUJI PHOTO FILM CO., LTD.; EP1362894; (2003); A2;,
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem