Reference of 85148-95-4, Adding some certain compound to certain chemical reactions, such as: 85148-95-4, name is 6-Formylpicolinonitrile,molecular formula is C7H4N2O, can increase the reaction rate and produce products with better performance than those obtained under traditional synthetic methods. Here is a downstream synthesis route of the compound 85148-95-4.
(1) 2,6-Dimethyl-4-(6-cyano-2-pyridyl)-1,4-dihydropyridine-3,5-dicarboxylic acid 3-beta-chloroethyl ester 5-methyl ester 6-Cyano-2-pyridine aldehyde (1.613 g, 12.2 mmol), chloroethyl acetoacetate (2.009 g, 12.2 mmol) and methyl 3-aminocrotonate (1.364 g, 12.2 mmol) were dissolved in 16 ml of isopropanol, and the solution was stirred at 35 to 40°C under a nitrogen gas stream for 14 hours. The reaction solvent was distilled off under reduced pressure, and the residue was purified by column chromatography [silica gel; ethyl acetate-n-hexane (5: 6)]. The crude product thus obtained was recrystallized from isopropyl ether-methanol to obtain 1.546 g (34percent yield) of the above-captioned compound.
According to the analysis of related databases, 85148-95-4, the application of this compound in the production field has become more and more popular.
Reference:
Patent; THE GREEN CROSS CORPORATION; EP216542; (1991); B1;,
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem