Pyridine is a basic heterocyclic organic compound with the chemical formula C5H5N. It is structurally related to benzene, with one methine group (=CH−) replaced by a nitrogen atom. 5315-25-3, formula is C6H6BrN, Name is 2-Bromo-6-methylpyridine. It is a highly flammable, weakly alkaline, water-miscible liquid with a distinctive, unpleasant fish-like smell. Reference of 5315-25-3.
Sharninghausen, Liam S.;Brooks, Allen F.;Winton, Wade P.;Makaravage, Katarina J.;Scott, Peter J. H.;Sanford, Melanie S. research published 《 NHC-Copper Mediated Ligand-Directed Radiofluorination of Aryl Halides》, the research content is summarized as follows. This report describes an aryl halides e.g., 2-(2-bromophenyl)pyridine radiofluorination reaction in which the C(sp2)-18F bond is formed e.g., 2-(2-fluorophenyl)pyridine-18F via a copper-mediated pathway. Copper N-heterocyclic carbene complexes e.g., I (Ar = 2,6-diisopropylphenyl) serve as mediators for this transformation, using aryl halide substrates with directing groups at the ortho position. This reaction is applied to the radiofluorination of electronically diverse aryl halide derivatives, including the bioactive mols. vismodegib analog II and PH089 III.
Reference of 5315-25-3, 2-Bromo-6-methylpyridine (2BMPy) is a bromopyridine derivative. It is formed when 2-chloro-6-methylpyridine is heated with bromotrimethylsilane. Its synthesis from various methods have been reported.
2-Bromo-6-methylpyridine is a building block in the preparation of nitrogen containing heterocyclic compounds.
2-Bromo-6-methylpyridine is an organic compound that belongs to the group of pyridinium halides. It is soluble in common solvents such as water, ethanol, and acetone. 2BMPy has been shown to act as a glutamate receptor antagonist and has been used in the study of glutamate receptors, including their subtypes. This chemical has also been shown to have antioxidant properties and can be used in the prevention of atherosclerosis., 5315-25-3.