Electric Literature of 94952-46-2, As we all know, there are many different methods for the synthesis of a compound, and people can choose the synthesis method that suits their own laboratory according to the actual situation. 94952-46-2, name is 1-(5-Chloropyridin-2-yl)ethanone, molecular formula is C7H6ClNO, The compound is widely used in many fields, so it is necessary to find a new synthetic route. The downstream synthesis method of this compound is introduced below.
1-(5-Chloropyridin-2-yl)ethanone (238 mg, 1.53 mmol) was dissolved in methanol (10 mL) at50 C. Sodium borohydride (174 mg, 4.5 mmol) was added portionwise and after addition was complete the reaction mixture was stirred at 50 C for 1 h. The solvent was removed,the residue was dissolved in water (10 mL), extracted with ethyl acetate (20 mL x 4) and the solvent evaporated from the combined organic phases to give 1-(5-chloropyridin-2-yl)ethanol as a colourless oil (201 mg, crude).
While traditionally a conservative industry, chemical producers will need to modernize their PR strategies to stay relevant.we look forward to future research findings about 94952-46-2, 1-(5-Chloropyridin-2-yl)ethanone.
Reference:
Patent; GLAXOSMITHKLINE INTELLECTUAL PROPERTY DEVELOPMENT LIMITED; BOUILLOT, Anne Marie Jeanne; DENIS, Alexis; LIDDLE, John; WALKER, Ann, Louise; (58 pag.)WO2016/188828; (2016); A1;,
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem