Adding a certain compound to certain chemical reactions, such as: 17075-15-9, 4-(Methylsulfonyl)pyridine, can increase the reaction rate and produce products with better performance than those obtained under traditional synthetic methods. Here is a downstream synthesis route of the compound, SDS of cas: 17075-15-9, blongs to pyridine-derivatives compound. SDS of cas: 17075-15-9
EXAMPLE 2A 4-[2-[4-(1,1-dimethylethoxy)phenyl]ethoxy]pyridine (Compound 9A) To a suspension of about one-half gram of 60% NaH (dispersion in oil) in 10 mL of dry DMF was added 1.5 g (0.0077 m) of 2-[4-(1,1-dimethylethoxy)phenyl]ethanol. The mixture was stirred in a warm water bath until hydrogen evolution ceased. After 30-40 minutes, 1 g (0.0064 m) of 4-(methylsulfonyl)pyridine in 5-7 mL of DMF was added. The mixture was stirred at room temperature overnight, then diluted with water. The product was extracted into CH2 Cl2, and the extracts were washed with saturated brine, filtered through phase separating paper, and concentrated in vacuo. The resulting material was azeotroped with xylene to remove excess DMF. This material was adsorbed onto silica gel and chromatographed over silica gel 60 (230-400 mesh) using CH2 Cl2 ?50% EtOAc/CH2 Cl2 to give the title product as an oil. Yield 0.7 g.
At the same time, in my other blogs, there are other synthetic methods of this type of compound,17075-15-9, 4-(Methylsulfonyl)pyridine, and friends who are interested can also refer to it.
Reference:
Patent; DowElanco; US5399564; (1995); A;,
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem