Synthetic Route of 59281-14-0, With the rapid development and complex challenges of chemical substances, the synthesis of new drugs is usually one of the most effective ways to increase yield.59281-14-0, name is 5-(Benzyloxy)-2-(hydroxymethyl)pyridin-4(1H)-one, molecular formula is C13H13NO3, molecular weight is 231.25, as common compound, the synthetic route is as follows.
General procedure: 20 mmol of compound 4 (4a-4f) was weighed into 100 mL of dichloromethane, Then add 0.16 mol of manganese dioxide, The mixed system was heated under reflux at 50 C in a oil bath for 72-96 h, and the TLC spot plate was used to detect the reaction process. After the reaction is over, The manganese dioxide was removed by suction filtration and the solvent 5 was evaporated to give compound 5.
Statistics shows that 59281-14-0 is playing an increasingly important role. we look forward to future research findings about 5-(Benzyloxy)-2-(hydroxymethyl)pyridin-4(1H)-one.
Reference:
Patent; Zhejiang Gongshang University; Zhou Tao; Shao Lele; (12 pag.)CN106986819; (2017); A;,
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem