Each compound has different characteristics, and only by selecting the characteristics of the compound suitable for a specific situation can the compound be applied on a large scale. 74784-70-6, name is 5-(Trifluoromethyl)pyridin-2-amine. This compound has unique chemical properties. The synthetic route is as follows. SDS of cas: 74784-70-6
Phenyl chloroformate (620mg, 3.96 mmol) was added to a solution of 5-(trifluoromethyl)pyridin-2-amine (615 mg, 3.79 mmol) and pyridine (323 mg, 4.08 mmol) in ACN (50 mL) at 0C. After stirring the solution overnight at room temperature, the reaction was quenched with H20. The resulting precipitate was filtered, dried and used without further purification. The product was a white solid (905mg, 3.21 mmol, 84% yield).
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Reference:
Patent; THE REGENTS OF THE UNIVERSITY OF CALIFORNIA; HAMMOCK, Bruce; KODANI, Sean; (110 pag.)WO2017/160861; (2017); A1;,
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem