Simple exploration of 5407-87-4

Statistics shows that 5407-87-4 is playing an increasingly important role. we look forward to future research findings about 2-Amino-4,6-dimethylpyridine.

With the rapid development and complex challenges of chemical substances, the synthesis of new drugs is usually one of the most effective ways to increase yield.5407-87-4, name is 2-Amino-4,6-dimethylpyridine, molecular formula is C7H10N2, molecular weight is 122.17, as common compound, the synthetic route is as follows.5407-87-4

The mixture of 4,6-dimethylpyridin-2-amine (1 g, 8.2 mmol, 1.0 eq) and NBS (1.46 g, 8.2 mmol, 1.0 eq) in CH3CN (30 mL) was stirred at rt overnight. Then the mixture was concentrated, and the residue was purified on silica gel column (PE/EtOAc = 5/1) to afford 5-bromo-4,6-dimethylpyridin-2-amine as a yellow solid (800 mg, 48%).

Statistics shows that 5407-87-4 is playing an increasingly important role. we look forward to future research findings about 2-Amino-4,6-dimethylpyridine.

Reference:
Patent; LIFESCI PHARMACEUTICALS, INC.; MCDONALD, Andrew; WO2015/103317; (2015); A1;,
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem