Reference of 158980-21-3, As we all know, there are many different methods for the synthesis of a compound, and people can choose the synthesis method that suits their own laboratory according to the actual situation. 158980-21-3, name is Ethyl 6-aminoimidazo[1,2-a]pyridine-2-carboxylate, molecular formula is C10H11N3O2, The compound is widely used in many fields, so it is necessary to find a new synthetic route. The downstream synthesis method of this compound is introduced below.
To a solution of ethyl 6-aminoimidazo[l,2-a]pyridine-2-carboxylate(A35, 1.0 g, 4.87 mmol) in pyridine(10 mL) methane sulphonyl chloride(0.37 mL, 4.87 mmol) was added and the resulting solution was stirred at room temperature for 2 h. After completion of reaction concentrated under reduced pressure to get crude. The crude was dissolved in DCM and washed with water and dried with anhydrous Na2S04, filtered and concentrated to afford ethyl 6-(methylsulfonamido)imidazo[l,2-a]pyridine-2-carboxylate 1-56 as a Light green solid. Yield: 0.70 g(crude) LC-MS(ES) m/z : 284.08[M+H]+.
While traditionally a conservative industry, chemical producers will need to modernize their PR strategies to stay relevant.we look forward to future research findings about 158980-21-3, Ethyl 6-aminoimidazo[1,2-a]pyridine-2-carboxylate.
Reference:
Patent; JUBILANT BIOSYS LIMITED; VADIVELU, Saravanan; RAJAGOPAL, Sridharan; BURRI, Raghunadha Reddy; GARAPATY, Shivani; SIVANANDHAN, Dhanalakshmi; THAKUR, Manish Kumar; NATARAJAN, Tamizharasan; SWAMY, Indu N; NAGARAJU, Nagendra; KANAGARAJ, Subramaniam; MOHD, Zainuddin; SARKAR, Sayantani; SAMANTA, Swapan Kumar; ., Hariprakash; (284 pag.)WO2019/102494; (2019); A1;,
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem