Pyridine has a conjugated system of six π electrons that are delocalized over the ring. 5315-25-3, formula is C6H6BrN, Name is 2-Bromo-6-methylpyridine. The molecule is planar and, thus, follows the Hückel criteria for aromatic systems. Reference of 5315-25-3.
Singh, Reena;Ganguly, Gaurab;Malinkin, Sergey O.;Demeshko, Serhiy;Meyer, Franc;Nordlander, Ebbe;Paine, Tapan Kanti research published 《 A Mononuclear Nonheme Iron(IV)-Oxo Complex of a Substituted N4Py Ligand: Effect of Ligand Field on Oxygen Atom Transfer and C-H Bond Cleavage Reactivity》, the research content is summarized as follows. A mononuclear iron(II) complex [FeII(N4PyMe2)(OTf)](OTf) (1), supported by a new pentadentate ligand, bis(6-methylpyridin-2-yl)-N,N-bis((pyridin-2-yl)methyl)methanamine (N4PyMe2), has been isolated and characterized. Introduction of Me groups in the 6-position of two pyridine rings makes the N4PyMe2 a weaker field ligand compared to the parent N4Py ligand. Complex 1 is high-spin in the solid state and converts to [FeII(N4PyMe2)(CH3CN)](OTf)2 (1a) in acetonitrile solution The iron(II) complex in acetonitrile displays temperature-dependent spin-crossover behavior over a wide range of temperature In its reaction with m-CPBA or oxone in acetonitrile at -10°, the iron(II) complex converts to an iron(IV)-oxo species, [FeIV(O)(N4PyMe2)]2+ (2). Complex 2 exhibits the Moessbauer parameters δ = 0.05 mm/s and ΔEq = 0.62 mm/s, typical of N-ligated S = 1 iron(IV)-oxo species. The iron(IV)-oxo complex has a half-life of only 14 min at 25° and is reactive toward oxygen-atom-transfer and hydrogen-atom-transfer (HAT) reactions. Compared to the parent complex [FeIV(O)(N4Py)]2+, 2 is more reactive in oxidizing thioanisole and oxygenates the C-H bonds of aliphatic substrates including that of cyclohexane. The enhanced reactivity of 2 toward cyclohexane results from the involvement of the S = 2 transition state in the HAT pathway and a lower triplet-quintet splitting compared to [FeIV(O)(N4Py)]2+, as supported by DFT calculations The second-order rate constants for HAT by 2 is well correlated with the C-H bond dissociation energies of aliphatic substrates. Surprisingly, the slope of this correlation is different from that of [FeIV(O)(N4Py)]2+, and 2 is more reactive only in the case of strong C-H bonds (>86 kcal/mol), but less reactive in the case of weaker C-H bonds. Using oxone as the oxidant, the iron(II) complex displays catalytic oxidations of substrates with low activity but with good selectivity.
Reference of 5315-25-3, 2-Bromo-6-methylpyridine (2BMPy) is a bromopyridine derivative. It is formed when 2-chloro-6-methylpyridine is heated with bromotrimethylsilane. Its synthesis from various methods have been reported.
2-Bromo-6-methylpyridine is a building block in the preparation of nitrogen containing heterocyclic compounds.
2-Bromo-6-methylpyridine is an organic compound that belongs to the group of pyridinium halides. It is soluble in common solvents such as water, ethanol, and acetone. 2BMPy has been shown to act as a glutamate receptor antagonist and has been used in the study of glutamate receptors, including their subtypes. This chemical has also been shown to have antioxidant properties and can be used in the prevention of atherosclerosis., 5315-25-3.