Non-covalent interactions governing the supramolecular assembly of copper(II) complexes with hydrazone-type ligand: Experimental and quantum chemical study was written by Singh, Y.;Patel, Ram N.;Patel, Satish K.;Jadeja, R. N.;Patel, Abhay K.;Patel, Neetu;Roy, H.;Kumar, P.;Butcher, R. J.;Jasinski, Jerry P.;Cortijo, M.;Herrero, S.. And the article was included in Polyhedron in 2021.Synthetic Route of C12H9NO This article mentions the following:
Two new mono- and one binuclear 娓?nitrato bridged Cu(II) complexes [Cu(L)(HL)]ClO4 (1), [Cu(HL)(NO3)(H2O)]2NO3閳ヮ敭2O (2) and [Cu2(L2)(娓?NO3)2] (3), with an unsym. NNO donor Schiff base (HL) were synthesized and characterized by elemental anal., FTIR, CV, UV-visible and EPR spectroscopy. Their mol. structures were also determined by single crystal x-ray crystallog. In the binuclear complex 3, the Cu璺矾璺?Cu distance is 3.494 鑴? In 1, 2 and 3, the Cu(II) centers have distorted square pyramidal geometry (锜?sub>5 = 0.05-0.17). Evidence of weak 锜鸿矾璺矾锜?stacking intermol. interactions along with other noncovalent interactions (H bonding) was observed by analyzing the resp. crystal structures of the complexes. Thus, these H bonds, 锜鸿矾璺矾锜?stacking interactions and other weak intermol. interactions establish as supramol. architectures a crystalline network environment. The noncovalent interactions were also studied by employing Hirshfeld Anal. The room temperature magnetic moments of the mononuclear complexes are less than the spin only values which are indicative of small interactions. Also, significant magnetic interactions were not exhibited by binuclear Cu(II) complex 3 in the variable temperature magnetic measurements. The X-band EPR spectra of all three complexes exhibit Cu(II) hyperfine structures as well as zero-field splitting which are appropriate for the triplet states of dimers. In 1 and 2, the presence of pseudo dipolar interactions is proposed. Quantum chem. calculations (DFT) were carried out on complexes 1–3 to explore the electronic and spectral properties of these newly synthesized complexes. These complexes show significant antiproliferative and SOD activity. The SOD activity measured in terms of kMcCF is in the range 4.94-12.31 (mol L)-1s-1 x 104. In the experiment, the researchers used many compounds, for example, Phenyl(pyridin-2-yl)methanone (cas: 91-02-1Synthetic Route of C12H9NO).
Phenyl(pyridin-2-yl)methanone (cas: 91-02-1) belongs to pyridine derivatives. Pyridine’s the lone pair does not contribute to the aromatic system but importantly influences the chemical properties of pyridine, as it easily supports bond formation via an electrophilic attack. Pyridine derivatives are also useful as small-molecule 浼?helix mimetics that inhibit protein-protein interactions, as well as functionally selective GABA ligands.Synthetic Route of C12H9NO