SDS of cas: 13534-97-9In 2010 ,《Switchable Cucurbituril-Bipyridine Beacons》 was published in Chemistry – A European Journal. The article was written by Sinha, Mantosh K.; Reany, Ofer; Parvari, Galit; Karmakar, Ananta; Keinan, Ehud. The article contains the following contents:
4-Aminobipyridine derivatives form strong inclusion complexes with cucurbit[6]uril, exhibiting remarkably large enhancements in fluorescence intensity and quantum yields. The remarkable complexation-induced pKa shift (ΔpKa=3.3) highlights the strong charge-dipole interaction upon binding. The reversible binding phenomenon can be used for the design of switchable beacons that can be incorporated into cascades of binding networks. This concept is demonstrated herein by three different applications: (1) a switchable fluorescent beacon for chem. sensing of transition metals and other ligands; (2) direct measurement of binding constants between cucurbit[6]uril and various nonfluorescent guest mols.; and (3) quant. monitoring of biocatalytic reactions and determination of their kinetic parameters. The latter application is illustrated by the hydrolysis of an amide catalyzed by penicillin G acylase and by the elimination reaction of a β-cabamoyloxy ketone catalyzed by aldolase antibody 38C2. The experimental process involved the reaction of 6-Bromopyridin-3-amine(cas: 13534-97-9SDS of cas: 13534-97-9)
6-Bromopyridin-3-amine(cas: 13534-97-9) belongs to anime. Large quantities of aliphatic amines are made synthetically. The most widely used industrial method is the reaction of alcohols with ammonia at a high temperature, catalyzed by metals or metal oxide catalysts (e.g., nickel or copper). Mixtures of primary, secondary, and tertiary amines are thereby produced.SDS of cas: 13534-97-9