108-48-5, Adding a certain compound to certain chemical reactions, such as: 108-48-5, 2,6-Dimethylpyridine, can increase the reaction rate and produce products with better performance than those obtained under traditional synthetic methods. Here is a downstream synthesis route of the compound, 108-48-5, blongs to pyridine-derivatives compound.
General procedure: To a stirred solution of substituted indoline-2,3-diones (1.0 mmol) in dioxane (1 mL) was added lutidines/picolines (2.5 mmol) and Iodine (20 mol %). The resulting mixture was heated at reflux for 8 h. After completion of the reaction, poured EtOAc and then washed with an ice cold saturated aqueous Na2S2O3 solution (10 mL¡Á2). Organic layer washed sequentially with brine, ice water and dried over anhydrous MgSO4. Evaporation of the organic solvent afforded the crude products, which was purified by silica gel column chromatography using n-hexane/ethyl acetate (4:1-1:1) as eluent to give desired products.
These compound has a wide range of applications. It is believed that with the continuous development of the source of the synthetic route,108-48-5, its application will become more common.
Reference:
Article; Vuppalapati, Srinivasu V.N.; Lee, Yong Rok; Tetrahedron; vol. 68; 39; (2012); p. 8286 – 8292;,
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem