Adding a certain compound to certain chemical reactions, such as: 127406-55-7, 4-Pyridin-3-yl-benzaldehyde, can increase the reaction rate and produce products with better performance than those obtained under traditional synthetic methods. Here is a downstream synthesis route of the compound, 127406-55-7, blongs to pyridine-derivatives compound. Recommanded Product: 127406-55-7
Methyl iodide (0. 8 ml, 12. 9 mmol) was added to a solution of 4- (3-PYRIDYL) benzaldehyde (0. 78 g, 4. 3 mmol) in dichloromethane and stirred 2 days. Additional methyl iodide (0. 8 ml, 12. 9 mmol) was added and stirred for 3 hr. After removal of the solvent, methanol was added to the residue and ice-cooled. Sodium tetrahydroborate (6. 4 g, 17. 0 mmol) was added to the solution and stirred for 1. 5 hr with warming to room temperature. Organic solvents were removed under reduced pressure after addition of water and extracted with ethyl acetate, washed with water and brine and dried over sodium sulfate. After removal of the solvent under reduced pressure, residue was purified by silica gel chromatography (eluent ethyl acetate to methanol) to give 3-(4-HYDROXYMETHYLPHENYL)-1-METHYL-1, 2, 5, 6- TETRAHYDROPYRIDINE (0. 63 g, 72%).
These compound has a wide range of applications. It is believed that with the continuous development of the source of the synthetic route,127406-55-7, its application will become more common.
Reference:
Patent; MITSUBISHI PHARMA CORPORATION; SANOFI-SYNTHELABO; WO2004/85408; (2004); A1;,
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem