With the rapid development and complex challenges of chemical substances, the synthesis of new drugs is usually one of the most effective ways to increase yield.6443-85-2, name is 2-(Pyridin-3-yl)acetonitrile, molecular formula is C7H6N2, molecular weight is 118.14, as common compound, the synthetic route is as follows.Formula: C7H6N2
54.1 Synthesis of 3-cyano-3-(pyridin-3-yl)-pentanedioic acid diethyl ester Prepare by the method of example 1.1.2 using pyridin-3-yl-acetonitrile (0.161 mol) and ethyl bromoacetate (0.325 mol). Chromatograph on silica gel to give the title compound.
At the same time, in my other blogs, there are other synthetic methods of this type of compound,6443-85-2, 2-(Pyridin-3-yl)acetonitrile, and friends who are interested can also refer to it.
Reference:
Patent; Merrell Pharmaceuticals Inc.; US5635510; (1997); A;,
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem