Each compound has different characteristics, and only by selecting the characteristics of the compound suitable for a specific situation can the compound be applied on a large scale. 132606-40-7, name is 5-Bromo-2-chloro-6-methylpyridine. This compound has unique chemical properties. The synthetic route is as follows. SDS of cas: 132606-40-7
3-Bromo-6-chloro-2-methylpyridine (200 mg, 0.969 mmol), tert-butyl (2-oxopiperidin-4-yl)carbamate (249 mg, 1.162 mmol), Pd2(dba)3(89 mg, 0.0972 mmol), Xantphos (112 mg, 0.194 mmol), cesium carbonate (947 mg, 2.907 mmol) were stirred in dioxane (10 mL) overnight at 100C under nitrogen, cooled and concentrated to give the product after column chromatography ( 31 mg, yield 9.4%).
If you are interested in these compounds, you can also browse my other articles.Thank you for taking the time to read this article. I hope you enjoyed it, 132606-40-7, 5-Bromo-2-chloro-6-methylpyridine.
Reference:
Patent; Shanghai Hansen Bio-pharmaceutical Technology Co., Ltd.; Jiangsu Haosen Pharmaceutical Group Co., Ltd.; Liu Shiqiang; Zhou Yuanfeng; Liu Lei; Bao Rudi; (47 pag.)CN107793399; (2018); A;,
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem