Application of 7598-26-7, Adding some certain compound to certain chemical reactions, such as: 7598-26-7, name is 5-Methyl-3-nitropyridin-2-amine,molecular formula is C6H7N3O2, can increase the reaction rate and produce products with better performance than those obtained under traditional synthetic methods. Here is a downstream synthesis route of the compound 7598-26-7.
Pd/C (50 mg, 0.47 mmol) was added to a stirred solution of 2-amino-5-methyl-3- nitropyridine (500 mg, 3.27 mmol) was in MeOH (7 ml). The reaction was then evacuated of air 3 times and filled with H2 gas. The reaction was then stirred under this atmosphere at 20C for 5 h after which the reaction was filtered through Celite and washed with further MeOH (30 ml). The solution was concentrated in vacuo to give WIN-321 -195-01 (395 mg, 98%). 1H NMR (MeOD): delta 7.22 (dd, J 2.0, 0.9 Hz, 1 H), 6.81 (dd, J 2.0, 0.7 Hz, 1 H), 2.13 (t, J 0.7 Hz, 3H). MS, m/z = 124 (100).
In the field of chemistry, the synthetic routes of compounds are constantly being developed and updated. I will also mention this compound in other articles. 7598-26-7, 5-Methyl-3-nitropyridin-2-amine, other downstream synthetic routes, hurry up and to see.
Reference:
Patent; THE UNIVERSITY OF MELBOURNE; THE WALTER AND ELIZA HALL INSTITUTE OF MEDICAL RESEARCH; SLEEBS, Brad; PURCELL, Damian Francis John; JACOBSON, Jonathan; LEWIN, Sharon; NGUYEN, William; (163 pag.)WO2017/219083; (2017); A1;,
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem