Patel, KPP; Gayakwad, EM; Shankarling, GS in [Patel, Khushbu P.; Gayakwad, Eknath M.; Shankarling, Ganapati S.] Inst Chem Technol, Dept Dyestuff Technol, NP Marg, Mumbai 400019, Maharashtra, India published Graphene oxide: a convenient metal-free carbocatalyst for facilitating amidation of esters with amines in 2020, Cited 49. Category: pyridine-derivatives. The Name is Ethyl nicotinate. Through research, I have a further understanding and discovery of 614-18-6.
Herein, we report a graphene oxide (GO) catalyzed condensation of non-activated esters and amines, that can enable diverse amides to be synthesized from abundant ethyl esters forming only volatile alcohol as a by-product. GO accelerates ester to amide conversion in the absence of any additives, unlike other catalysts. A wide range of ester and amine substrates are screened to yield the respective amides in good to excellent yields. The improved catalytic activity can be ascribed to the oxygenated functionalities present on the graphene oxide surface which forms H-bonding with the reactants accelerating the reaction. Improved yields and a wide range of functional group tolerance are some of the important features of the developed protocol.
Category: pyridine-derivatives. About Ethyl nicotinate, If you have any questions, you can contact Patel, KPP; Gayakwad, EM; Shankarling, GS or concate me.
Reference:
Pyridine – Wikipedia,
,Pyridine | C5H5N – PubChem