626-64-2, The major producers of chemicals have been the Europe, Japan and China. Due to the growing call for a cleaner, greener environment, people will have to find innovative ways to maintain their relevance. Here is a compound 626-64-2, name is Pyridin-4-ol. This compound has unique chemical properties. The synthetic route is as follows.
9.5 g (0.10 mol) of 4-hydroxypyridine,, 21.5 g (0.11 mol) of 4-bromobutyric acid ethyl ester,0.5 g of 5% Pd / C catalyst,80 ml of ethanol was placed in a 300 ml autoclave, and the interior of the container was replaced with hydrogen.While introducing hydrogen gas into the vessel, the reactor was heated to 100 C. while stirring, and the reaction was carried out at a hydrogen pressure of 4.9 ¡Á 10 5 Pa for 9 hours.After allowing the reactor to cool down, disappearance of 4-hydroxypyridine was confirmed by TLC. The catalyst was removed by filtration, and the obtained reaction solution was concentrated.To the residue was added 100 ml of water and extracted with 60 ml of ethyl acetate, and the organic layer was dried and concentrated. After drying the obtained solid under reduced pressure, 18.3 g (85 mmol, yield 85%) of (4-hydroxy) -4-piperidinobutanoic acid ethyl ester was obtained.
While traditionally a conservative industry, chemical producers will need to modernize their PR strategies to stay relevant.we look forward to future research findings about 626-64-2, Pyridin-4-ol.
Reference:
Patent; TOKUYAMA CORPORATION; SEKI, MASAHIKO; YAMAMOTO, HIROMASA; (13 pag.)JP2018/24593; (2018); A;,
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem