Related Products of 70201-43-3 ,Some common heterocyclic compound, 70201-43-3, molecular formula is C6H4BrNO, its traditional synthetic route has been very mature, but the traditional synthetic route has various shortcomings, such as complicated route, low yield, poor purity, etc., below Introduce a new synthetic route.
General procedure: To a 50 mL round-bottomed flask charged with pentahydratedbismuth nitrate (0.032 g, 0.065 mmol) in ethanol(20 mL) were added thiobarbituric acid (0.144 g, 1.0 mmol) and aromatic aldehydes (1.0 mmol). The reaction mixturewas stirred for 10-20 min at 80 C, when thin layer chromatographyanalyzes revealed it was completed. Aftercompletion the precipitated product was separated by filtration,dried, and recrystallized from ethanol. Full physicaland spectroscopic data and yields for all compounds arepresented in the supporting information (SI).
These compound has a wide range of applications. It is believed that with the continuous development of the source of the synthetic route,70201-43-3, its application will become more common.
Reference:
Article; Shabeer, Muhammad; Barbosa, Luiz C. A.; Karak, Milandip; Coelho, Amanda C. S.; Takahashi, Jacqueline A.; Medicinal Chemistry Research; vol. 27; 4; (2018); p. 1043 – 1049;,
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