Application of 76102-92-6, Adding some certain compound to certain chemical reactions, such as: 76102-92-6, name is 2-Amino-N-(pyridin-3-yl)benzamide,molecular formula is C12H11N3O, can increase the reaction rate and produce products with better performance than those obtained under traditional synthetic methods. Here is a downstream synthesis route of the compound 76102-92-6.
Example 11 To a solution of 397 mg of 2-morpholin-4-yl-1,3-oxazole-4-carboxylic acid and 450 mul of 4-methylmorpholine in 10 ml of THF was added 260 mul of isobutyl chloroformate under ice-cooling, followed by stirring at room temperature for 30 minutes. Under ice-cooling, a solution of 426 mg of 2-amino-N-pyridin-3-yl benzamide in 8 ml of THF was added thereto, followed by stirring at room temperature for 1 hour and at 60C overnight. The reaction mixture was concentrated under reduced pressure, water was then added thereto, and the precipitated solid was collected by filtration. This was suspended in ethanol, and 1.5 ml of a 4 M hydrogen chloride/EtOAc solution was added thereto, followed by stirring for 2 hours. The solid in the system was collected by filtration to prepare 250 mg of 2-morpholin-4-yl-N-[2-(pyridin-3-ylcarbamoyl)phenyl]-1,3-oxazole-4-carboxamide hydrochloride.
According to the analysis of related databases, 76102-92-6, the application of this compound in the production field has become more and more popular.
Reference:
Patent; Astellas Pharma Inc.; EP2206707; (2010); A1;,
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem