Some scientific research about Ethyl 3-(2,6-Dichloro-5-fluoro-3-pyridyl)-3-oxopropionate

Statistics shows that 96568-04-6 is playing an increasingly important role. we look forward to future research findings about Ethyl 3-(2,6-Dichloro-5-fluoro-3-pyridyl)-3-oxopropionate.

Application of 96568-04-6, With the rapid development and complex challenges of chemical substances, the synthesis of new drugs is usually one of the most effective ways to increase yield.96568-04-6, name is Ethyl 3-(2,6-Dichloro-5-fluoro-3-pyridyl)-3-oxopropionate, molecular formula is C10H8Cl2FNO3, molecular weight is 280.08, as common compound, the synthetic route is as follows.

Ethyl 3-(2,6-dichloro-5-fluoropyridin-3-yl)-3-oxopropanoate (40 g) and triethyl orthoformate (26.1 mL) in acetic anhydride (100 mL) were stirred at 85 C. for 6.5 hours, cooled, and concentrated. The concentrate was crystallized from hexanes with a small amount of diethyl ether and dichloromethane.

Statistics shows that 96568-04-6 is playing an increasingly important role. we look forward to future research findings about Ethyl 3-(2,6-Dichloro-5-fluoro-3-pyridyl)-3-oxopropionate.

Reference:
Patent; Hinman, Mira M.; Rosenberg, Teresa A.; Wagner, Rolf; US2005/234053; (2005); A1;,
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem