Some scientific research about Reference of 13466-43-8

The chemical industry reduces the impact on the environment during synthesis 13466-43-8, I believe this compound will play a more active role in future production and life.

Reference of 13466-43-8, With the rapid development and complex challenges of chemical substances, the synthesis of new drugs is usually one of the most effective ways to increase yield.13466-43-8, name is 3-Bromopyridin-2(1H)-one, molecular formula is C5H4BrNO, molecular weight is 174, as common compound, the synthetic route is as follows.

Following a previously reported method (Meana A, et al, Synlett 2003,1678-1682) compound 18 was prepared from N-iodosuccinimide (2.48 g, 11.0 mmol) and 3-bromo-2-hydroxypyridine 17 (1.74 g, 10.0 mmol) as a pale brown solid ( 2.55 g, 85%). 1H NMR (DMSO-(I6) delta 12.21 (br s, IH), 8.08 (d, IH, J= 2.3 Hz), 7.71 (d, IH, J= 2.3 Hz).

The chemical industry reduces the impact on the environment during synthesis 13466-43-8, I believe this compound will play a more active role in future production and life.

Reference:
Patent; THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA; WO2007/126733; (2007); A2;,
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem