Some tips on 2-Methoxy-5-nitronicotinic acid

At the same time, in my other blogs, there are other synthetic methods of this type of compound,1020635-54-4, 2-Methoxy-5-nitronicotinic acid, and friends who are interested can also refer to it.

With the rapid development and complex challenges of chemical substances, the synthesis of new drugs is usually one of the most effective ways to increase yield.1020635-54-4, name is 2-Methoxy-5-nitronicotinic acid, molecular formula is C7H6N2O5, molecular weight is 198.13, as common compound, the synthetic route is as follows.HPLC of Formula: C7H6N2O5

2-Methoxy-5-nitro-nicotinic acid (36 mmol) and phosphorous pentachloride (72 mmol) were heated at 100 0C for 2h, The excess reagent was removed in vacuo to give an oily residue.

At the same time, in my other blogs, there are other synthetic methods of this type of compound,1020635-54-4, 2-Methoxy-5-nitronicotinic acid, and friends who are interested can also refer to it.

Reference:
Patent; BIONOMICS LIMITED; WO2008/46135; (2008); A1;,
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem