Related Products of 56673-34-8, With the rapid development and complex challenges of chemical substances, the synthesis of new drugs is usually one of the most effective ways to increase yield.56673-34-8, name is 3-Bromo-6-mercaptopyridine, molecular formula is C5H4BrNS, molecular weight is 190.06, as common compound, the synthetic route is as follows.
Weigh 0.591 g of Nd (OTf) 3, 0.33 g of tetraacetylated fucose,0.19 g of 5-bromo-2-mercaptopyridine in a parallel reaction tube. Nitrogen atmosphere were added 10mL1,2-dichloroethane, ionic liquid PFIL-2 [R1, R2, R3 = phenyl,n = 4, X = (CF3SO2) 2N] 0.5mL, the reaction tube was sealed, the reaction was stirred,Microwave irradiation using intermittent, power 500W,Each irradiation for 5 minutes, stop irradiation for 1 minute. Reaction for 5 hours,Temperature control at 80 degrees Celsius. The reaction was terminated by adding water.Separation by silica gel column gave 0.336 g of glycoside 1 in 73% yield.Ionic liquids can be reused, no significant change in yield.
Statistics shows that 56673-34-8 is playing an increasingly important role. we look forward to future research findings about 3-Bromo-6-mercaptopyridine.
Reference:
Patent; Ningbo University; Chen Weiting; (9 pag.)CN106397507; (2017); A;,
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