Application of 65-22-5, The major producers of chemicals have been the Europe, Japan and China. Due to the growing call for a cleaner, greener environment, people will have to find innovative ways to maintain their relevance. Here is a compound 65-22-5, name is 3-Hydroxy-5-(hydroxymethyl)-2-methylisonicotinaldehyde hydrochloride. This compound has unique chemical properties. The synthetic route is as follows.
2.2.1 PLSC·2H2O Semicarbazide hydrogenchloride (1.07 g, 10 mmol) was dissolved in warm H2O (10 mL), to which a warm solution of pyridoxal hydrogenchloride (2.00 g, 10 mmol) in H2O (10 mL) was added. To this solution Na2CO3·10H2O (3.00 g, 15 mmol) dissolved in H2O (10 mL) was added in portions, and the mixture was mildly heated for a couple of minutes. The obtained solution was left at room temperature for about 20 h, after which the single crystals were filtered and washed with H2O. Yield: 2.30 g (88%). Anal. Calc. for C9H16N4O5: C, 41.54; H, 6.20; N, 21.53. Found: C, 41.43; H, 6.16; N, 21.50%. Selected IR bands [ /cm-1]: 3466, 3381, nu(OH), nu(NH2); 3202, nu(NH); 2850, nu(NH+); 1697, 1678, nu(C=O); 1583, nu(CN); 1280, nu(COphenolic). UV-Vis (DMF) [lambdamax/nm (log epsilon/M-1 cm-1)]: 289 (4.12), 298sh (4.08), 327bp (3.75) (sh-shoulder, bp-broad peak).
According to the analysis of related databases, 65-22-5, the application of this compound in the production field has become more and more popular.
Reference:
Article; Vojinovi?-Je?i?, Ljiljana S.; Jovanovi?, Ljiljana S.; Leovac, Vukadin M.; Radanovi?, Mirjana M.; Rodi?, Marko V.; Barta Hollo, Berta; Meszasaros Szecsenyi, Katalin; Ivkovi?, Sonja A.; Polyhedron; vol. 101; (2015); p. 196 – 205;,
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem