Application of 165547-79-5, The major producers of chemicals have been the Europe, Japan and China. Due to the growing call for a cleaner, greener environment, people will have to find innovative ways to maintain their relevance. Here is a compound 165547-79-5, name is 4-Chloro-3-nitro-2(1H)-pyridinone. This compound has unique chemical properties. The synthetic route is as follows.
Methyl iodide (2.06 mL, 32.99 mmol) was added to a suspension of 4-chloro-2-hydroxy-3-nitropyridine (prepared as described in Bioorg. Med. Chem. Lett., 2003, 13, 125) (2.87 g, 16.49 mmol) and silver carbonate (4.55 g, 16.49 mmol) in toluene (100 mL) and the mixture heated at 85 C. for 3.5 h. On cooling to ambient temperature the mixture was filtered through dicalite and washed with toluene. The combined filtrate and washings were concentrated in vacuo and the crude product purified by chromatography on silica gel with EtOAc:heptane (1:9, v/v) as eluent. The pure product was collected as a white solid (1.99 g, 64%).Data for 4-chloro-2-hydroxy-3-nitropyridine: MS (ESI) m/z:189/191 ([M+H]+).
While traditionally a conservative industry, chemical producers will need to modernize their PR strategies to stay relevant.we look forward to future research findings about 165547-79-5, 4-Chloro-3-nitro-2(1H)-pyridinone.
Reference:
Patent; N.V. Organon; US2007/112019; (2007); A1;,
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem