Adding a certain compound to certain chemical reactions, such as: 31181-53-0, 5-Fluoro-2-methylpyridine, can increase the reaction rate and produce products with better performance than those obtained under traditional synthetic methods. Here is a downstream synthesis route of the compound, 31181-53-0, blongs to pyridine-derivatives compound. Computed Properties of C6H6FN
1 5-Fluoro-2-pyridinecarboxylic acid To water (100 ml) were added 5-fluoro-2-methylpyridine (J. Med. Chem., 32, 1970(1989): 2.2 g, 20 mmol) and potassium permanganate (19.1 g, 120 mmol), and heated under reflux for 4 hours. The reaction mixture was filtrated and the filtrate was concentrated, acidified with KHSO4, extracted with ethyl acetate and the extract was dried over Na2SO4. The sol vent was evaporated to give the title compound (0.80 g; 28%). 1H-NMR(270 MHz, DMSO-d6) 8.70 (d, J=2.8 Hz, 1H), 8.14 (dd, J=8.7, 4.6 Hz, 1H), 7.89 (td, J=8.7, 2.8 Hz, 1H)
These compound has a wide range of applications. It is believed that with the continuous development of the source of the synthetic route,31181-53-0, its application will become more common.
Reference:
Patent; Sumitomo Pharmaceuticals Company, Limited; US6384033; (2002); B1;,
Pyridine – Wikipedia,
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