624-28-2, The major producers of chemicals have been the Europe, Japan and China. Due to the growing call for a cleaner, greener environment, people will have to find innovative ways to maintain their relevance. Here is a compound 624-28-2, name is 2,5-Dibromopyridine. This compound has unique chemical properties. The synthetic route is as follows.
Preparation 55 4-(5-Bromo-pvridin-2-vl)-morpholine; 2,5-Dibromopyridine (7.1 g, 30 mmol), morpholine (1.74 mL, 20 mmol), cesium carbonate (9.1 g, 28 mmol), tris (dibenzylideneacetone) dipalladium (0) (183 mg, 0.2 mmol), and racemic 2,2′-bis (diphenylphosphino)-1, 1′-binaphthyl (374 mg, 0.6 mmol) in toluene (20 mL) was heated at 120C for 24 hours. After cooling to room temperature, the mixture was filtered through CeliteT””and the Celte tu pad was washed with chloroform. The solution was concentrated in vacuo and was purified by silica gel chromatography (200: 1 chloroform- methanol) to give 2.9 g (60% yield) of the title compound. 13C NMR (100 MHz, CD03) d 158.3, 148. 7, 140.0, 108. 4, 66.8, 45.7 ; MS (AP/Cl) 243.0, 245.0 (M+H) +
While traditionally a conservative industry, chemical producers will need to modernize their PR strategies to stay relevant.we look forward to future research findings about 624-28-2, 2,5-Dibromopyridine.
Reference:
Patent; PFIZER PRODUCTS INC.; WO2005/90300; (2005); A1;,
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